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Journal of the American Podiatric Medical Association, Vol 80, Issue 1 3-8, Copyright © 1990 by American Podiatric Medical Association

JOURNAL ARTICLE

Epidemiology and pathogenesis of HIV infection. Approaching the second decade

SL Becker
Department of Medicine, California College of Podiatric Medicine, San Francisco 94115.

Human immunodeficiency virus (HIV) is a retrovirus that can be transmitted through sexual activity, blood products, and perinatal exposure. The virus is composed of core, transmembrane, and envelope proteins. Cells of the immune system are the primary target of HIV, and destruction of the immune response is characteristic of end-stage disease. Although male homosexuals continue to represent the largest population of persons with acquired immunodeficiency syndrome (AIDS), transmission among intravenous drug users accounts for the rapidly growing incidence of pediatric and heterosexual AIDS patients. Control of the epidemic among intravenous drug users is the major challenge in the US today.




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Copyright © 1990 by the American Podiatric Medical Association.