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Journal of the American Podiatric Medical Association, Vol 80, Issue 5 266-270, Copyright © 1990 by American Podiatric Medical Association

CLINICAL TRIAL

Comparison of flurbiprofen and acetaminophen with codeine in postoperative foot pain

ML Ottinger, KW Kinney, JR Black and M Wittenberg
American College of Foot Surgeons, Augusta, GA.

The purpose of this double-blind, randomized, parallel, multiple-dose study was to compare the efficacy and safety of flurbiprofen with acetaminophen with codeine phosphate in the 96-hr postoperative period following foot surgery. Analysis of mean pain intensity and mean pain relief for the patients not requiring rescue medication did not reveal any significant differences between treatment groups. There were also no significant differences between treatment groups with respect to patient and investigator global evaluations of therapy. The incidence of termination of the study because of side effects was higher for the acetaminophen with codeine group.


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M. A. Turlik, D. Kushner, and D. Stock
Assessing the Validity of Published Randomized Controlled Trials in Podiatric Medical Journals
J Am Podiatr Med Assoc, September 1, 2003; 93(5): 392 - 398.
[Abstract] [Full Text] [PDF]


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Copyright © 1990 by the American Podiatric Medical Association.