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Journal of the American Podiatric Medical Association, Vol 84, Issue 12 614-621, Copyright © 1994 by American Podiatric Medical Association

JOURNAL ARTICLE

Aloe vera, hydrocortisone, and sterol influence on wound tensile strength and anti-inflammation

RH Davis, JJ DiDonato, RW Johnson and CB Stewart
Pennsylvania College of Podiatric Medicine, Philadelphia.

Aloe vera at doses of 100 and 300 mg/kg daily for 4 days blocked the wound healing suppression of hydrocortisone acetate up to 100% using the wound tensile strength assay. This response was because of the growth factors present in A. vera masking the wound healing inhibitors such as sterols and certain amino acids. The sterols showed good anti-inflammatory activity (-36%) in reducing the croton oil-induced ear swelling. This activity displayed a dose-response relationship.


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[Abstract] [Full Text]


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Copyright © 1994 by the American Podiatric Medical Association.