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Journal of the American Podiatric Medical Association, Vol 84, Issue 2 77-81, Copyright © 1994 by American Podiatric Medical Association


JOURNAL ARTICLE

Anti-inflammatory and wound healing activity of a growth substance in Aloe vera

RH Davis, JJ Donato, GM Hartman and RC Haas
Department of Biomedical Sciences, Pennsylvania College of Podiatric Medicine, Philadelphia.

Aloe vera improves wound healing and inhibits inflammation. Since mannose-6-phosphate is the major sugar in the Aloe gel, the authors examined the possibility of its being an active growth substance. Mice receiving 300 mg/kg of mannose-6-phosphate had improved wound healing over saline controls. This dose also had anti-inflammatory activity. The function of mannose-6-phosphate in A. vera is discussed.


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