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Journal of the American Podiatric Medical Association, Vol 84, Issue 7 348-354, Copyright © 1994 by American Podiatric Medical Association

CLINICAL TRIAL

Comparison of piroxicam and naproxen in osteoarthritis of the foot

MB Jennings
New York College of Podiatric Medicine, New York.

Osteoarthritis is the most common joint disease and the second highest ranking cause of disability in the US. Osteoarthritis commonly affects the hands, wrists, spine, knees, and feet. One of the mainstays of treatment for osteoarthritis is the use of nonsteroidal anti-inflammatory drugs. While there have been controlled comparison studies of the various nonsteroidal anti-inflammatory drugs, these have been limited to osteoarthritis of the hands, spine, and hip. This study was a randomized, double-blind, parallel study of 8 weeks' duration comparing piroxicam (Feldene, 20 mg daily) to naproxen (Naprosyn, 1,000 mg daily) in the treatment of osteoarthritis of the foot in 45 patients. Both groups experienced significant pain relief and improvement of mobility.


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M. A. Turlik, D. Kushner, and D. Stock
Assessing the Validity of Published Randomized Controlled Trials in Podiatric Medical Journals
J Am Podiatr Med Assoc, September 1, 2003; 93(5): 392 - 398.
[Abstract] [Full Text] [PDF]


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Copyright © 1994 by the American Podiatric Medical Association.