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Journal of the American Podiatric Medical Association, Vol 87, Issue 11 520-531, Copyright © 1997 by American Podiatric Medical Association
JOURNAL ARTICLE |
WS Joseph
Pennsylvania College of Podiatric Medicine, Philadelphia 19107, USA.
The author discusses the new oral antifungal agents for the treatment of onychomycosis. The history, mechanisms of action, efficacies, dosing, safety profiles, and costs of itraconazole, terbinafine, and fluconazole are reviewed. The author emphasizes that use of these effective antifungals represents an important paradigm shift for podiatric physicians away from the palliative therapy of nail debridement to a potentially curative treatment.
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