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Fluoroquinolone Therapy and Achilles Tendon Rupture

Diane Vanek, BS^*, Amol Saxena, DPM and John M. Boggs, MD

^* California School of Podiatric Medicine, San Francisco.
Department of Sports Medicine, Palo Alto Medical Foundation, Palo Alto, CA.
Department of Internal Medicine and Infectious Diseases, Palo Alto Medical Foundation, Palo Alto, CA.

Corresponding author: Amol Saxena, DPM, Department of Sports Medicine, Palo Alto Medical Foundation, 795 El Camino Real, Palo Alto, CA 94301.

Abstract

Fluoroquinolones have been associated with tendinopathies. The authors present three cases of Achilles tendinopathy in which the patients’ symptoms were preceded by treatment for unrelated bacterial infections with ciprofloxacin. Although the exact mechanism of the relationship is not understood, those who engage in sports or exercise should be advised of the risk of quinolone-induced tendinopathy. (J Am Podiatr Med Assoc 93(4): 333-335, 2003)

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