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Journal of the American Podiatric Medical Association
Volume 93 Number 5 373-379 2003
Copyright © 2003 American Podiatric Medical Association

Satisfaction with Onychomycosis Treatment

Pulse versus Continuous Dosing

Erin M. Warshaw, MD*, Thomas Bowman, DPM{dagger}, Myron A. Bodman, DPM{ddagger}, John J. Kim, PharmD§, Stefanie Silva, MS|| and Susan D. Mathias, MPH||

* Minneapolis Veterans Affairs Medical Center, Minneapolis, MN.
{dagger} North Oaks Podiatry, Dalton, GA.
{ddagger} Ohio College of Podiatric Medicine, Cleveland.
§ Duke University, Durham, NC. Dr. Kim is now with Amgen Inc, Thousand Oaks, CA.
|| Quintiles Late Phase, San Francisco, CA. Ms. Mathias is now with Ovation Research Group, Highland Park, IL.

Corresponding author: Erin M. Warshaw, MD, Minneapolis Veterans Affairs Medical Center, Dermatology/IIIK, One Veterans Dr, Minneapolis, MN 55417.

Abstract

The purpose of this study, which involved two dermatology clinics and two podiatric medical clinics, was to determine whether a difference exists in patient-reported satisfaction and compliance between continuous terbinafine therapy and pulse-dose itraconazole therapy for the treatment of toenail onychomycosis. Patients in this multicenter, open-label, cross-sectional study had previously completed treatment with either oral terbinafine or oral itraconazole for toenail onychomycosis. Patients were interviewed by telephone to assess clinical outcomes, compliance, and satisfaction with treatment; clinical data were collected by medical chart review. Patients reported significantly greater ease and convenience of treatment and higher overall satisfaction with continuous terbinafine therapy compared with pulse-dose itraconazole therapy. (J Am Podiatr Med Assoc 93(5): 373-379, 2003)






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Copyright © 2003 by the American Podiatric Medical Association.