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Refraction Effects of Diffraction-Enhanced Radiographic Imaging

A New Look at Bone

Carol Muehleman, PhD ^* , Dale R. Sumner, PhD ^*  and Zhong Zhong, PhD 

^* Department of Anatomy and Cell Biology, Rush Medical College, Chicago, IL.
Department of Biochemistry, Rush Medical College, Chicago, IL.
Department of Orthopedic Surgery, Rush Medical College, Chicago, IL.
National Synchrotron Light Source, Brookhaven National Laboratory, Upton, NY.

Corresponding author: Carol Muehleman, PhD, Department of Anatomy and Cell Biology, Rush Medical College, ACFAC 507, 600 S Paulina St, Chicago, IL 60612.

Abstract

The objective of this study was to demonstrate the ability of a novel radiographic technology—diffraction-enhanced imaging—to detect contrast in bone tissue through absorption, refraction, and scatter rejection. Diffraction-enhanced imaging uses a synchrotron x-ray beam to produce images of high contrast by measuring the object’s refraction and ultra-small angle scattering of x-rays in addition to the attenuation measured by conventional radiography. We present evidence that diffraction-enhanced imaging provides contrast enhancement at the edges of cortical and cancellous bone and a three-dimensional appearance of trabeculae. (J Am Podiatr Med Assoc 94(5): 453–455, 2004)