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Treatment for Simple Plantar Verrucae

Monochloroacetic Acid and 10% Formaldehyde versus 10% Formaldehyde Alone

Maureen B. Jennings, DPM ^*, James Ricketti, DPM , John Guadara, DPM , Wendy Nach, DPM  and Susan Goodwin, PhD ^¶

^* Department of Medicine, New York College of Podiatric Medicine, New York, NY. Dr. Jennings is now with the Jennings Institute for Clinical Research in Fort Lee, NJ.
Private practice, Hamilton Square, NJ.
Private practice, Hackensack, NJ.
Private practice, Fair Lawn, NJ.
^¶ The Learning Center, New York Medical College, Valhalla.

Corresponding author: Maureen B. Jennings, DPM, Jennings Institute for Clinical Research, 1063 Palisades Ave, Fort Lee, NJ 07024.

Abstract

Verrucae are small, benign, highly vascular epithelial neoplasms that occur singly or in a multiple presentation. Plantar verrucae are usually caused by infection with human papillomavirus types 1, 2, and 4. A clinical trial was conducted to assess the safety and efficacy of monochloroacetic acid and 10% formaldehyde versus 10% formaldehyde alone in the treatment of simple plantar verrucae. Of 57 patients enrolled in the study, 26 were in the monochloroacetic acid and 10% formaldehyde group and 31 were in the 10% formaldehyde alone group. The overall cure rate for this population was 61.4%. There was no statistically significant difference in the cure rate between treatment groups. (J Am Podiatr Med Assoc 96(1): 53–58, 2006)