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Journal of the American Podiatric Medical Association
Volume 96 Number 2 116-119 2006
Copyright © 2006 American Podiatric Medical Association

Topical and Oral Combination Therapy for Toenail Onychomycosis

An Updated Review

Ivan R. Bristow, MSc(Oxon) * and Robert Baran, MD {dagger}

* School of Health Professions and Rehabilitation Sciences, University of Southampton, Southampton, England.
{dagger} Nail Disease Centre, Cannes, France.

Corresponding author: Ivan R. Bristow, MSc(Oxon), School of Health Professions and Rehabilitation Sciences, University of Southampton, Bldg 45, Highfield, Southampton, Hampshire SO17 1BJ, England.

Abstract

Although effective, oral antifungal therapy is still not completely successful. Recent studies have shown that combination therapy with oral and topical agents offers an increased cure rate for patients. We review the main drug combinations that have been tested. Additional measures, such as mechanical intervention, may help improve response rates further. (J Am Podiatr Med Assoc 96(2): 116–119, 2006)






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Copyright © 2006 by the American Podiatric Medical Association.