This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Yazgan, P. Articles by Baba, F. Search for Related Content PubMed PubMed Citation Articles by Yazgan, P. Articles by Baba, F.

Third Metatarsal Brown Tumor with Secondary Hyperparathyroidism

An Atypical Localization

Pelin Yazgan, MD ^*, Adil Ozturk, MD , Ismahan Orhan, MD ^*, Ocal Sirmatel, MD  and Fusun Baba, MD 

^* Physical Medicine and Rehabilitation, Harran University, Sanliurfa, Turkey.
Radiology, Harran University, Sanliurfa, Turkey.
Pathology, Harran University, Sanliurfa, Turkey.

Corresponding author: Pelin Yazgan, MD, Physical Medicine and Rehabilitation, Harran University, Arastirma ve Uygulama Hastanesi, Sanliurfa, 63100, Turkey.

Abstract

Brown tumors represent the terminal stage of the remodeling process during primary or secondary hyperparathyroidism. We report the first case of brown tumor on the third metatarsal associated with secondary hyperparathyroidism caused by vitamin D deficiency. Radiography showed an expansile tissue mass in the third metatarsal bone. The diagnosis was suggested by the clinical history and was confirmed by biochemical, radiologic, and histopathologic determinations. After intravenous therapy with calcidiol, 1g/d, her symptoms were relieved. The brown tumor showed regression and ossification during the 3 months after therapy. (J Am Podiatr Med Assoc 98(4): 314–317, 2008)